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Multicellular Human Cardiac Organoids Transcriptomically Model Distinct Tissue-Level Features of Adult Myocardium

Human-induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) have been widely used for disease modeling and drug cardiotoxicity screening. To this end, we recently developed human cardiac organoids (hCOs) for modeling human myocardium. Here, we perform a transcriptomic analysis of various...

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Detalles Bibliográficos
Autores principales: Kerr, Charles M., Richards, Dylan, Menick, Donald R., Deleon-Pennell, Kristine Y., Mei, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8395156/
https://www.ncbi.nlm.nih.gov/pubmed/34445185
http://dx.doi.org/10.3390/ijms22168482