Inhibition of Autotaxin and Lysophosphatidic Acid Receptor 5 Attenuates Neuroinflammation in LPS-Activated BV-2 Microglia and a Mouse Endotoxemia Model

Increasing evidence suggests that systemic inflammation triggers a neuroinflammatory response that involves sustained microglia activation. This response has deleterious consequences on memory and learning capability in experimental animal models and in patients. However, the mechanisms connecting s...

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Detalles Bibliográficos
Autores principales: Joshi, Lisha, Plastira, Ioanna, Bernhart, Eva, Reicher, Helga, Triebl, Alexander, Köfeler, Harald C., Sattler, Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8395174/
https://www.ncbi.nlm.nih.gov/pubmed/34445223
http://dx.doi.org/10.3390/ijms22168519

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8395174/
https://www.ncbi.nlm.nih.gov/pubmed/34445223
http://dx.doi.org/10.3390/ijms22168519

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