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The SCF Complex Is Essential to Maintain Genome and Chromosome Stability

The SKP1, CUL1, F-box protein (SCF) complex encompasses a group of 69 SCF E3 ubiquitin ligase complexes that primarily modify protein substrates with poly-ubiquitin chains to target them for proteasomal degradation. These SCF complexes are distinguishable by variable F-box proteins, which determine...

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Detalles Bibliográficos
Autores principales: Thompson, Laura L., Rutherford, Kailee A., Lepage, Chloe C., McManus, Kirk J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8395177/
https://www.ncbi.nlm.nih.gov/pubmed/34445249
http://dx.doi.org/10.3390/ijms22168544