Tamoxifen Application Is Associated with Transiently Increased Loss of Hippocampal Neurons following Virus Infection

Tamoxifen is frequently used in murine knockout systems with CreER/LoxP. Besides possible neuroprotective effects, tamoxifen is described as having a negative impact on adult neurogenesis. The present study investigated the effect of a high-dose tamoxifen application on Theiler’s murine encephalomye...

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Detalles Bibliográficos
Autores principales: Hülskötter, Kirsten, Lühder, Fred, Flügel, Alexander, Herder, Vanessa, Baumgärtner, Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8395206/
https://www.ncbi.nlm.nih.gov/pubmed/34445189
http://dx.doi.org/10.3390/ijms22168486

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8395206/
https://www.ncbi.nlm.nih.gov/pubmed/34445189
http://dx.doi.org/10.3390/ijms22168486

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