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Evaluation of Interactions of Selected Olivacine Derivatives with DNA and Topoisomerase II

Olivacine and ellipticine are model anticancer drugs acting as topoisomerase II inhibitors. Here, we present investigations performed on four olivacine derivatives in light of their antitumor activity. The aim of this study was to identify the best antitumor compound among the four tested olivacine...

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Detalles Bibliográficos
Autores principales: Tylińska, Beata, Dobosz, Agnieszka, Spychała, Jan, Cwynar-Zając, Łucja, Czyżnikowska, Żaneta, Kuźniarski, Amadeusz, Gębarowski, Tomasz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8395211/
https://www.ncbi.nlm.nih.gov/pubmed/34445198
http://dx.doi.org/10.3390/ijms22168492