Co-Aggregation of S100A9 with DOPA and Cyclen-Based Compounds Manifested in Amyloid Fibril Thickening without Altering Rates of Self-Assembly

The amyloid cascade is central for the neurodegeneration disease pathology, including Alzheimer’s and Parkinson’s, and remains the focus of much current research. S100A9 protein drives the amyloid-neuroinflammatory cascade in these diseases. DOPA and cyclen-based compounds were used as amyloid modif...

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Detalles Bibliográficos
Autores principales: Arabuli, Lili, Iashchishyn, Igor A., Romanova, Nina V., Musteikyte, Greta, Smirnovas, Vytautas, Chaudhary, Himanshu, Svedružić, Željko M., Morozova-Roche, Ludmilla A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8395260/
https://www.ncbi.nlm.nih.gov/pubmed/34445262
http://dx.doi.org/10.3390/ijms22168556

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8395260/
https://www.ncbi.nlm.nih.gov/pubmed/34445262
http://dx.doi.org/10.3390/ijms22168556

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