Cargando…
Co-Aggregation of S100A9 with DOPA and Cyclen-Based Compounds Manifested in Amyloid Fibril Thickening without Altering Rates of Self-Assembly
The amyloid cascade is central for the neurodegeneration disease pathology, including Alzheimer’s and Parkinson’s, and remains the focus of much current research. S100A9 protein drives the amyloid-neuroinflammatory cascade in these diseases. DOPA and cyclen-based compounds were used as amyloid modif...
Autores principales: | Arabuli, Lili, Iashchishyn, Igor A., Romanova, Nina V., Musteikyte, Greta, Smirnovas, Vytautas, Chaudhary, Himanshu, Svedružić, Željko M., Morozova-Roche, Ludmilla A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8395260/ https://www.ncbi.nlm.nih.gov/pubmed/34445262 http://dx.doi.org/10.3390/ijms22168556 |
Ejemplares similares
-
Polyoxometalates
as Effective Nano-inhibitors of Amyloid
Aggregation of Pro-inflammatory S100A9 Protein Involved in Neurodegenerative
Diseases
por: Chaudhary, Himanshu, et al.
Publicado: (2021) -
Natural Compound from Olive Oil Inhibits S100A9 Amyloid
Formation and Cytotoxicity: Implications for Preventing Alzheimer’s
Disease
por: Leri, Manuela, et al.
Publicado: (2021) -
Templating S100A9 amyloids on Aβ fibrillar surfaces revealed by charge detection mass spectrometry, microscopy, kinetic and microfluidic analyses
por: Pansieri, Jonathan, et al.
Publicado: (2020) -
Methylene blue inhibits nucleation and elongation of SOD1 amyloid fibrils
por: Musteikyte, Greta, et al.
Publicado: (2020) -
Chaperones mainly suppress primary nucleation during formation of functional amyloid required for bacterial biofilm formation
por: Nagaraj, Madhu, et al.
Publicado: (2021)