Novel 2-(Adamantan-1-ylamino)Thiazol-4(5H)-One Derivatives and Their Inhibitory Activity towards 11β-HSD1—Synthesis, Molecular Docking and In Vitro Studies

A common mechanism in which glucocorticoids participate is suggested in the pathogenesis of such metabolic diseases as obesity, metabolic syndrome, or Cushing’s syndrome. The enzyme involved in the control of the availability of cortisol, the active form of the glucocorticoid for the glucocorticoid...

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Detalles Bibliográficos
Autores principales: Studzińska, Renata, Kupczyk, Daria, Płaziński, Wojciech, Baumgart, Szymon, Bilski, Rafał, Paprocka, Renata, Kołodziejska, Renata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8395285/
https://www.ncbi.nlm.nih.gov/pubmed/34445315
http://dx.doi.org/10.3390/ijms22168609

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8395285/
https://www.ncbi.nlm.nih.gov/pubmed/34445315
http://dx.doi.org/10.3390/ijms22168609

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