Cathepsin L, a Target of Hypoxia-Inducible Factor-1-α, Is Involved in Melanosome Degradation in Melanocytes

Hypoxic conditions induce the activation of hypoxia-inducible factor-1α (HIF-1α) to restore the supply of oxygen to tissues and cells. Activated HIF-1α translocates into the nucleus and binds to hypoxia response elements to promote the transcription of target genes. Cathepsin L (CTSL) is a lysosomal...

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Detalles Bibliográficos
Autores principales: Kim, Ji Young, Lee, Eun Jung, Ahn, Yuri, Park, Sujin, Bae, Yu Jeong, Kim, Tae Gyun, Oh, Sang Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8395286/
https://www.ncbi.nlm.nih.gov/pubmed/34445307
http://dx.doi.org/10.3390/ijms22168596

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8395286/
https://www.ncbi.nlm.nih.gov/pubmed/34445307
http://dx.doi.org/10.3390/ijms22168596

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