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Structural Water Stabilizes Protein Motifs in Liquid Protein Phase: The Folding Mechanism of Short β-Sheets Coupled to Phase Transition

Macromolecular associates, such as membraneless organelles or lipid-protein assemblies, provide a hydrophobic environment, i.e., a liquid protein phase (LP), where folding preferences can be drastically altered. LP as well as the associated phase change from water (W) is an intriguing phenomenon rel...

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Detalles Bibliográficos
Autores principales: Papp, Dóra, Szigyártó, Imola Csilla, Nordén, Bengt, Perczel, András, Beke-Somfai, Tamás
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8395295/
https://www.ncbi.nlm.nih.gov/pubmed/34445303
http://dx.doi.org/10.3390/ijms22168595