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Approaches to Enhance Precise CRISPR/Cas9-Mediated Genome Editing

Modification of the human genome has immense potential for preventing or treating disease. Modern genome editing techniques based on CRISPR/Cas9 show great promise for altering disease-relevant genes. The efficacy of precision editing at CRISPR/Cas9-induced double-strand breaks is dependent on the r...

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Detalles Bibliográficos
Autores principales: Denes, Christopher E., Cole, Alexander J., Aksoy, Yagiz Alp, Li, Geng, Neely, Graham Gregory, Hesselson, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8395304/
https://www.ncbi.nlm.nih.gov/pubmed/34445274
http://dx.doi.org/10.3390/ijms22168571