Sirolimus Suppresses Phosphorylation of Cofilin and Reduces Interstitial Septal Thickness in Sporadic Lymphangioleiomyomatosis

Sporadic lymphangioleiomyomatosis (S-LAM) is a rare lung disease characterized by the proliferation of smooth muscle-like LAM cells and progressive cystic destruction. Sirolimus, a mammalian target of rapamycin (mTOR) inhibitor, has a proven efficacy in patients with LAM. However, the therapeutic me...

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Detalles Bibliográficos
Autores principales: Huang, Yen-Lin, Chen, Po-Ru, Lai, Ying-Ju, Hsu, Hsao-Hsun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8395305/
https://www.ncbi.nlm.nih.gov/pubmed/34445268
http://dx.doi.org/10.3390/ijms22168564

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8395305/
https://www.ncbi.nlm.nih.gov/pubmed/34445268
http://dx.doi.org/10.3390/ijms22168564

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