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Small Molecule Receptor Binding Inhibitors with In Vivo Efficacy against Botulinum Neurotoxin Serotypes A and E

Botulinum neurotoxins (BoNTs) are the most poisonous substances in nature. Currently, the only therapy for botulism is antitoxin. This therapy suffers from several limitations and hence new therapeutic strategies are desired. One of the limitations in discovering BoNT inhibitors is the absence of an...

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Detalles Bibliográficos
Autores principales: Ben David, Alon, Barnea, Ada, Diamant, Eran, Dor, Eyal, Schwartz, Arieh, Torgeman, Amram, Zichel, Ran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8395308/
https://www.ncbi.nlm.nih.gov/pubmed/34445283
http://dx.doi.org/10.3390/ijms22168577