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Membrane Association Modes of Natural Anticancer Peptides: Mechanistic Details on Helicity, Orientation, and Surface Coverage

Anticancer peptides (ACPs) could potentially offer many advantages over other cancer therapies. ACPs often target cell membranes, where their surface mechanism is coupled to a conformational change into helical structures. However, details on their binding are still unclear, which would be crucial t...

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Detalles Bibliográficos
Autores principales: Quemé-Peña, Mayra, Juhász, Tünde, Kohut, Gergely, Ricci, Maria, Singh, Priyanka, Szigyártó, Imola Cs., Papp, Zita I., Fülöp, Lívia, Beke-Somfai, Tamás
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8395313/
https://www.ncbi.nlm.nih.gov/pubmed/34445319
http://dx.doi.org/10.3390/ijms22168613