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The Significance of the DUF283 Domain for the Activity of Human Ribonuclease Dicer

Dicers are multidomain proteins, usually comprising an amino-terminal putative helicase domain, a DUF283 domain (domain of unknown function), a PAZ domain, two RNase III domains (RNase IIIa and RNase IIIb) and a dsRNA-binding domain. Dicer homologs play an important role in the biogenesis of small r...

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Detalles Bibliográficos
Autores principales: Szczepanska, Agnieszka, Wojnicka, Marta, Kurzynska-Kokorniak, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8395393/
https://www.ncbi.nlm.nih.gov/pubmed/34445396
http://dx.doi.org/10.3390/ijms22168690