T-Cell Responses in Merkel Cell Carcinoma: Implications for Improved Immune Checkpoint Blockade and Other Therapeutic Options

Merkel cell carcinoma (MCC) is a rare and aggressive skin cancer with rising incidence and high mortality. Approximately 80% of the cases are caused by the human Merkel cell polyomavirus, while the remaining 20% are induced by UV light leading to mutations. The standard treatment of metastatic MCC i...

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Detalles Bibliográficos
Autores principales: Gehrcken, Laura, Sauerer, Tatjana, Schaft, Niels, Dörrie, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8395396/
https://www.ncbi.nlm.nih.gov/pubmed/34445385
http://dx.doi.org/10.3390/ijms22168679

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8395396/
https://www.ncbi.nlm.nih.gov/pubmed/34445385
http://dx.doi.org/10.3390/ijms22168679

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