PI3-Kinase p110α Deficiency Modulates T Cell Homeostasis and Function and Attenuates Experimental Allergic Encephalitis in Mature Mice

Class I phosphoinositide 3-kinases (PI3K) are involved in the development of normal and autoimmune responses, including Experimental Autoimmune Encephalomyelitis (EAE), a mouse model for human multiple sclerosis (MS). Here, the role of the ubiquitously expressed class IA PI3K p110α catalytic subunit...

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Detalles Bibliográficos
Autores principales: Rojo, José M., Montes-Casado, María, Aragoneses-Fenoll, Laura, Ojeda, Gloria, Dianzani, Umberto, Portolés, Pilar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8395417/
https://www.ncbi.nlm.nih.gov/pubmed/34445401
http://dx.doi.org/10.3390/ijms22168698

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8395417/
https://www.ncbi.nlm.nih.gov/pubmed/34445401
http://dx.doi.org/10.3390/ijms22168698

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