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PI3-Kinase p110α Deficiency Modulates T Cell Homeostasis and Function and Attenuates Experimental Allergic Encephalitis in Mature Mice
Class I phosphoinositide 3-kinases (PI3K) are involved in the development of normal and autoimmune responses, including Experimental Autoimmune Encephalomyelitis (EAE), a mouse model for human multiple sclerosis (MS). Here, the role of the ubiquitously expressed class IA PI3K p110α catalytic subunit...
Autores principales: | Rojo, José M., Montes-Casado, María, Aragoneses-Fenoll, Laura, Ojeda, Gloria, Dianzani, Umberto, Portolés, Pilar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8395417/ https://www.ncbi.nlm.nih.gov/pubmed/34445401 http://dx.doi.org/10.3390/ijms22168698 |
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