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Optimizing the Expression of Human Dopamine Receptors in Escherichia coli

The human dopamine receptors D(2S) and D(3) belong to the group of G protein-coupled receptors (GPCRs) and are important drug targets. Structural analyses and development of new receptor subtype specific drugs have been impeded by low expression yields or receptor instability. Fusing the T4 lysozyme...

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Detalles Bibliográficos
Autores principales: Boritzki, Vanessa, Hübner, Harald, Allikalt, Anni, Gmeiner, Peter, Wöhrl, Birgitta M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8395450/
https://www.ncbi.nlm.nih.gov/pubmed/34445358
http://dx.doi.org/10.3390/ijms22168647