Epitope Mapping of Monoclonal Antibodies to Calreticulin Reveals That Charged Amino Acids Are Essential for Antibody Binding

Calreticulin is a chaperone protein, which is associated with myeloproliferative diseases. In this study, we used resin-bound peptides to characterize two monoclonal antibodies (mAbs) directed to calreticulin, mAb FMC 75 and mAb 16, which both have significantly contributed to understanding the biol...

Descripción completa

Detalles Bibliográficos
Autores principales: Bergmann, Ann Christina, Kyllesbech, Cecilie, Slibinskas, Rimantas, Ciplys, Evaldas, Højrup, Peter, Trier, Nicole Hartwig, Houen, Gunnar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8395503/
https://www.ncbi.nlm.nih.gov/pubmed/34449535
http://dx.doi.org/10.3390/antib10030031

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8395503/
https://www.ncbi.nlm.nih.gov/pubmed/34449535
http://dx.doi.org/10.3390/antib10030031

Ejemplares similares