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Evaluation of Class IIa Histone Deacetylases Expression and In Vivo Epigenetic Imaging in a Transgenic Mouse Model of Alzheimer’s Disease

Epigenetic regulation by histone deacetylase (HDAC) is associated with synaptic plasticity and memory formation, and its aberrant expression has been linked to cognitive disorders, including Alzheimer’s disease (AD). This study aimed to investigate the role of class IIa HDAC expression in AD and mon...

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Detalles Bibliográficos
Autores principales: Chen, Yi-An, Lu, Cheng-Hsiu, Ke, Chien-Chih, Chiu, Sain-Jhih, Chang, Chi-Wei, Yang, Bang-Hung, Gelovani, Juri G., Liu, Ren-Shyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8395513/
https://www.ncbi.nlm.nih.gov/pubmed/34445342
http://dx.doi.org/10.3390/ijms22168633