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mTOR Knockdown in the Infralimbic Cortex Evokes A Depressive-like State in Mouse

Fast and sustained antidepressant effects of ketamine identified the mammalian target of rapamycin (mTOR) signaling pathway as the main modulator of its antidepressive effects. Thus, mTOR signaling has become integral for the preclinical evaluation of novel compounds to treat depression. However, ca...

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Detalles Bibliográficos
Autores principales: Garro-Martínez, Emilio, Fullana, Maria Neus, Florensa-Zanuy, Eva, Senserrich, Julia, Paz, Verónica, Ruiz-Bronchal, Esther, Adell, Albert, Castro, Elena, Díaz, Álvaro, Pazos, Ángel, Bortolozzi, Analía, Pilar-Cuéllar, Fuencisla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8395521/
https://www.ncbi.nlm.nih.gov/pubmed/34445375
http://dx.doi.org/10.3390/ijms22168671