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mTOR Knockdown in the Infralimbic Cortex Evokes A Depressive-like State in Mouse
Fast and sustained antidepressant effects of ketamine identified the mammalian target of rapamycin (mTOR) signaling pathway as the main modulator of its antidepressive effects. Thus, mTOR signaling has become integral for the preclinical evaluation of novel compounds to treat depression. However, ca...
Autores principales: | Garro-Martínez, Emilio, Fullana, Maria Neus, Florensa-Zanuy, Eva, Senserrich, Julia, Paz, Verónica, Ruiz-Bronchal, Esther, Adell, Albert, Castro, Elena, Díaz, Álvaro, Pazos, Ángel, Bortolozzi, Analía, Pilar-Cuéllar, Fuencisla |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8395521/ https://www.ncbi.nlm.nih.gov/pubmed/34445375 http://dx.doi.org/10.3390/ijms22168671 |
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