Cargando…

Rational Design of Constrained Peptides as Protein Interface Inhibitors

The lack of progress in developing targeted therapeutics directed at protein–protein complexes has been due to the absence of well-defined ligand-binding pockets and the extensive intermolecular contacts at the protein–protein interface. Our laboratory has developed approaches to dissect protein–pro...

Descripción completa

Detalles Bibliográficos
Autores principales: Murali, Ramachandran, Zhang, Hongtao, Cai, Zheng, Lam, Lian, Greene, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8395526/
https://www.ncbi.nlm.nih.gov/pubmed/34449551
http://dx.doi.org/10.3390/antib10030032