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Membrane-Disrupting Molecules as Therapeutic Agents: A Cautionary Note
[Image: see text] Mechanistic studies have shown that aggregates of a common membrane disrupting molecule, Triton X-100, destroy the integrity of cholesterol-rich phospholipid bilayers via a catastrophic rupture process. In sharp contrast, attack on such membranes by monomers of Triton X-100 destroy...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American
Chemical Society
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8395607/ https://www.ncbi.nlm.nih.gov/pubmed/34467266 http://dx.doi.org/10.1021/jacsau.0c00037 |