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A DNA Aptamer That Inhibits the Aberrant Signaling of Fibroblast Growth Factor Receptor in Cancer Cells

[Image: see text] Growth factor receptors are activated through dimerization by the binding of their ligands and play pivotal roles in normal cell function. However, the aberrant activity of the receptors has been associated with cancer malignancy. One of the main causes of the aberrant receptor act...

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Detalles Bibliográficos
Autores principales: Eguchi, Akihiro, Ueki, Ayaka, Hoshiyama, Junya, Kuwata, Keiko, Chikaoka, Yoko, Kawamura, Takeshi, Nagatoishi, Satoru, Tsumoto, Kouhei, Ueki, Ryosuke, Sando, Shinsuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8395645/
https://www.ncbi.nlm.nih.gov/pubmed/34467321
http://dx.doi.org/10.1021/jacsau.0c00121