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A DNA Aptamer That Inhibits the Aberrant Signaling of Fibroblast Growth Factor Receptor in Cancer Cells
[Image: see text] Growth factor receptors are activated through dimerization by the binding of their ligands and play pivotal roles in normal cell function. However, the aberrant activity of the receptors has been associated with cancer malignancy. One of the main causes of the aberrant receptor act...
Autores principales: | Eguchi, Akihiro, Ueki, Ayaka, Hoshiyama, Junya, Kuwata, Keiko, Chikaoka, Yoko, Kawamura, Takeshi, Nagatoishi, Satoru, Tsumoto, Kouhei, Ueki, Ryosuke, Sando, Shinsuke |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8395645/ https://www.ncbi.nlm.nih.gov/pubmed/34467321 http://dx.doi.org/10.1021/jacsau.0c00121 |
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