Entropy–Entropy Compensation between the Protein, Ligand, and Solvent Degrees of Freedom Fine-Tunes Affinity in Ligand Binding to Galectin-3C

[Image: see text] Molecular recognition is fundamental to biological signaling. A central question is how individual interactions between molecular moieties affect the thermodynamics of ligand binding to proteins and how these effects might propagate beyond the immediate neighborhood of the binding...

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Detalles Bibliográficos
Autores principales: Wallerstein, Johan, Ekberg, Vilhelm, Ignjatović, Majda Misini, Kumar, Rohit, Caldararu, Octav, Peterson, Kristoffer, Wernersson, Sven, Brath, Ulrika, Leffler, Hakon, Oksanen, Esko, Logan, Derek T., Nilsson, Ulf J., Ryde, Ulf, Akke, Mikael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8395690/
https://www.ncbi.nlm.nih.gov/pubmed/34467311
http://dx.doi.org/10.1021/jacsau.0c00094

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8395690/
https://www.ncbi.nlm.nih.gov/pubmed/34467311
http://dx.doi.org/10.1021/jacsau.0c00094

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