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Endogenous Conjugation of Biomimetic Dinitrosyl Iron Complex with Protein Vehicles for Oral Delivery of Nitric Oxide to Brain and Activation of Hippocampal Neurogenesis

[Image: see text] Nitric oxide (NO), a pro-neurogenic and antineuroinflammatory gasotransmitter, features the potential to develop a translational medicine against neuropathological conditions. Despite the extensive efforts made on the controlled delivery of therapeutic NO, however, an orally active...

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Príomhchruthaitheoirí: Wu, Cheng-Ru, Huang, Yi-Da, Hong, Yong-Huei, Liu, Ya-Hsin, Narwane, Manmath, Chang, Yu-Hsiang, Dinh, Trinh Kieu, Hsieh, Hsin-Tzu, Hseuh, Yi-Jen, Wu, Ping-Ching, Pao, Chih-Wen, Chan, Ting-Shan, Hsu, I-Jui, Chen, Yunching, Chen, Hung-Chi, Chin, Ting-Yu, Lu, Tsai-Te
Formáid: Online Alt Téacs
Teanga:English
Foilsithe / Cruthaithe: American Chemical Society 2021
Rochtain ar líne:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8395708/
https://www.ncbi.nlm.nih.gov/pubmed/34467346
http://dx.doi.org/10.1021/jacsau.1c00160