Investigation of the Complexes Formed between PARP1 Inhibitors and PARP1 G-Quadruplex at the Gene Promoter Region

DNA repair inhibitors are one of the latest additions to cancer chemotherapy. In general, chemotherapy produces DNA damage but tumoral cells may become resistant if enzymes involved in DNA repair are overexpressed and are able to reverse DNA damage. One of the most successful drugs based on modulati...

Descripción completa

Detalles Bibliográficos
Autores principales: Dallavalle, Sabrina, Princiotto, Salvatore, Mattio, Luce M., Artali, Roberto, Musso, Loana, Aviñó, Anna, Eritja, Ramon, Pisano, Claudio, Gargallo, Raimundo, Mazzini, Stefania
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8395737/
https://www.ncbi.nlm.nih.gov/pubmed/34445442
http://dx.doi.org/10.3390/ijms22168737

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8395737/
https://www.ncbi.nlm.nih.gov/pubmed/34445442
http://dx.doi.org/10.3390/ijms22168737

Ejemplares similares