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Effects of Rapamycin on Insulin Brain Endothelial Cell Binding and Blood–Brain Barrier Transport

Rapamycin is an exogenous compound that has been shown to improve cognition in Alzheimer’s disease mouse models and can regulate pathways downstream of the insulin receptor signaling pathway. Insulin is also known to improve cognition in rodent models of Alzheimer’s disease. Central nervous system (...

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Detalles Bibliográficos
Autores principales: Nguyen, Steven, Banks, William A., Rhea, Elizabeth M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8395935/
https://www.ncbi.nlm.nih.gov/pubmed/34449653
http://dx.doi.org/10.3390/medsci9030056