Betulin Sulfonamides as Carbonic Anhydrase Inhibitors and Anticancer Agents in Breast Cancer Cells

Hypoxia-regulated protein carbonic anhydrase IX (CA IX) is up-regulated in different tumor entities and correlated with poor prognosis in breast cancer patients. Due to the radio- and chemotherapy resistance of solid hypoxic tumors, derivatives of betulinic acid (BA), a natural compound with antican...

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Detalles Bibliográficos
Autores principales: Güttler, Antje, Eiselt, Yvonne, Funtan, Anne, Thiel, Andreas, Petrenko, Marina, Keßler, Jacqueline, Thondorf, Iris, Paschke, Reinhard, Vordermark, Dirk, Bache, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8395940/
https://www.ncbi.nlm.nih.gov/pubmed/34445506
http://dx.doi.org/10.3390/ijms22168808

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8395940/
https://www.ncbi.nlm.nih.gov/pubmed/34445506
http://dx.doi.org/10.3390/ijms22168808

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