Direct Synthesis of Polyaromatic Cyclophanes Containing Bis-Methylene-Interrupted Z-Double Bonds and Study of Their Antitumor Activity In Vitro

An original synthetic route was developed for the preparation of previously unknown unsaturated polyaromatic macrolactones containing a 1Z,5Z-diene moiety in 48–71% yields and with >98% stereoselectivity. The method is based on intermolecular cyclocondensation of aromatic dicarboxylic acids with...

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Detalles Bibliográficos
Autores principales: D’yakonov, Vladimir A., Islamov, Ilgiz I., Dzhemileva, Lilya U., Makarova, Elina Kh., Dzhemilev, Usein M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8396040/
https://www.ncbi.nlm.nih.gov/pubmed/34445489
http://dx.doi.org/10.3390/ijms22168787

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8396040/
https://www.ncbi.nlm.nih.gov/pubmed/34445489
http://dx.doi.org/10.3390/ijms22168787

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