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A Michael Acceptor Analogue, SKSI-0412, Down-Regulates Inflammation and Proliferation Factors through Suppressing Signal Transducer and Activator of Transcription 3 Signaling in IL-17A-Induced Human Keratinocyte

The activation of signal transducer and activator of transcription 3 (STAT3), as well as up-regulation of cytokines and growth factors to promote STAT3 activation, have been found in the epidermis of psoriatic lesions. Recently, a series of synthetic compounds possessing the Michael acceptor have be...

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Detalles Bibliográficos
Autores principales: Kim, A-Ram, Lee, Seungbeom, Shin, Jung U, Seok, Seung Hui, Suh, Young-Ger, Kim, Dong Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8396041/
https://www.ncbi.nlm.nih.gov/pubmed/34445513
http://dx.doi.org/10.3390/ijms22168813