CFH Loss in Human RPE Cells Leads to Inflammation and Complement System Dysregulation via the NF-κB Pathway

Age-related macular degeneration (AMD), the leading cause of vision loss in the elderly, is a degenerative disease of the macula, where retinal pigment epithelium (RPE) cells are damaged in the early stages of the disease, and chronic inflammatory processes may be involved. Besides aging and lifesty...

Descripción completa

Detalles Bibliográficos
Autores principales: Armento, Angela, Schmidt, Tiziana L., Sonntag, Inga, Merle, David A., Jarboui, Mohamed Ali, Kilger, Ellen, Clark, Simon J., Ueffing, Marius
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8396051/
https://www.ncbi.nlm.nih.gov/pubmed/34445430
http://dx.doi.org/10.3390/ijms22168727

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8396051/
https://www.ncbi.nlm.nih.gov/pubmed/34445430
http://dx.doi.org/10.3390/ijms22168727

Ejemplares similares