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Dual-modality loop-mediated isothermal amplification for pretreatment-free detection of Septin9 methylated DNA in colorectal cancer

Currently, the determination of DNA methylation is still a challenge due to the limited efficiency of enrichment, bisulfite modification, and detection. In this study, a dual-modality loop-mediated isothermal amplification integrated with magnetic bead isolation is  proposed for the determination of...

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Detalles Bibliográficos
Autores principales: Lin, Qiuyuan, Fang, Xueen, Chen, Hui, Weng, Wenhao, Liu, Baohong, Kong, Jilie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Vienna 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8396143/
https://www.ncbi.nlm.nih.gov/pubmed/34453211
http://dx.doi.org/10.1007/s00604-021-04979-8