CSF Proteomic Alzheimer’s Disease-Predictive Subtypes in Cognitively Intact Amyloid Negative Individuals

We recently discovered three distinct pathophysiological subtypes in Alzheimer’s disease (AD) using cerebrospinal fluid (CSF) proteomics: one with neuronal hyperplasticity, a second with innate immune system activation, and a third subtype with blood–brain barrier dysfunction. It remains unclear whe...

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Detalles Bibliográficos
Autores principales: Tijms, Betty Marije, Gobom, Johan, Teunissen, Charlotte, Dobricic, Valerija, Tsolaki, Magda, Verhey, Frans, Popp, Julius, Martinez-Lage, Pablo, Vandenberghe, Rik, Lleó, Alberto, Molinuévo, José Luís, Engelborghs, Sebastiaan, Freund-Levi, Yvonne, Froelich, Lutz, Bertram, Lars, Lovestone, Simon, Streffer, Johannes, Vos, Stephanie, , ADNI, Blennow, Kaj, Scheltens, Philip, Zetterberg, Henrik, Visser, Pieter Jelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8396164/
https://www.ncbi.nlm.nih.gov/pubmed/34449748
http://dx.doi.org/10.3390/proteomes9030036

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8396164/
https://www.ncbi.nlm.nih.gov/pubmed/34449748
http://dx.doi.org/10.3390/proteomes9030036

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