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Endocytic Protein Defects in the Neural Crest Cell Lineage and Its Pathway Are Associated with Congenital Heart Defects

Endocytic trafficking is an under-appreciated pathway in cardiac development. Several genes related to endocytic trafficking have been uncovered in a mutagenic ENU screen, in which mutations led to congenital heart defects (CHDs). In this article, we review the relationship between these genes (incl...

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Detalles Bibliográficos
Autores principales: Arrigo, Angelo B., Lin, Jiuann-Huey Ivy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8396181/
https://www.ncbi.nlm.nih.gov/pubmed/34445520
http://dx.doi.org/10.3390/ijms22168816