17,20S(OH)(2)pD Can Prevent the Development of Skin Fibrosis in the Bleomycin-Induced Scleroderma Mouse Model

Systemic sclerosis (SSc; scleroderma) is a chronic fibrotic disease involving TGF-β1. Low serum vitamin D (vit D) correlates with the degree of fibrosis and expression of TGF-β1. This study was designed to determine whether the noncalcemic vit D analog, 17,20S(OH)(2)pD, suppresses fibrosis and media...

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Detalles Bibliográficos
Autores principales: Brown Lobbins, Monica L., Scott, Imara-Safi O., Slominski, Andrzej T., Hasty, Karen A., Zhang, Sicheng, Miller, Duane D., Li, Wei, Kim, Tae-Kang, Janjetovic, Zorica, Patel, Tejesh S., Myers, Linda K., Postlethwaite, Arnold E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8396226/
https://www.ncbi.nlm.nih.gov/pubmed/34445632
http://dx.doi.org/10.3390/ijms22168926

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8396226/
https://www.ncbi.nlm.nih.gov/pubmed/34445632
http://dx.doi.org/10.3390/ijms22168926

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