Myelin Defects in Niemann–Pick Type C Disease: Mechanisms and Possible Therapeutic Perspectives

Niemann–Pick type C (NPC) disease is a wide-spectrum clinical condition classified as a neurovisceral disorder affecting mainly the liver and the brain. It is caused by mutations in one of two genes, NPC1 and NPC2, coding for proteins located in the lysosomes. NPC proteins are deputed to transport c...

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Detalles Bibliográficos
Autores principales: Bernardo, Antonietta, De Nuccio, Chiara, Visentin, Sergio, Martire, Alberto, Minghetti, Luisa, Popoli, Patrizia, Ferrante, Antonella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8396228/
https://www.ncbi.nlm.nih.gov/pubmed/34445564
http://dx.doi.org/10.3390/ijms22168858

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8396228/
https://www.ncbi.nlm.nih.gov/pubmed/34445564
http://dx.doi.org/10.3390/ijms22168858

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