Involvement of Oxidative and Endoplasmic Reticulum Stress in RDH12-Related Retinopathies

Retinol dehydrogenase 12 (RDH12) is expressed in photoreceptor inner segments and catalyses the reduction of all-trans retinal (atRAL) to all-trans retinol (atROL), as part of the visual cycle. Mutations in RDH12 are primarily associated with autosomal recessive Leber congenital amaurosis. To furthe...

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Detalles Bibliográficos
Autores principales: Sarkar, Hajrah, Toms, Maria, Moosajee, Mariya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8396253/
https://www.ncbi.nlm.nih.gov/pubmed/34445569
http://dx.doi.org/10.3390/ijms22168863

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8396253/
https://www.ncbi.nlm.nih.gov/pubmed/34445569
http://dx.doi.org/10.3390/ijms22168863

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