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Generalizable Compositional Features Influencing the Proteostatic Fates of Polar Low-Complexity Domains

Protein aggregation is associated with a growing list of human diseases. A substantial fraction of proteins in eukaryotic proteomes constitutes a proteostasis network—a collection of proteins that work together to maintain properly folded proteins. One of the overarching functions of the proteostasi...

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Detalles Bibliográficos
Autores principales: Cascarina, Sean M., Kaplan, Joshua P., Elder, Mikaela R., Brookbank, Lindsey, Ross, Eric D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8396281/
https://www.ncbi.nlm.nih.gov/pubmed/34445649
http://dx.doi.org/10.3390/ijms22168944