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R-Loops and Its Chro-Mates: The Strange Case of Dr. Jekyll and Mr. Hyde
Since their discovery, R-loops have been associated with both physiological and pathological functions that are conserved across species. R-loops are a source of replication stress and genome instability, as seen in neurodegenerative disorders and cancer. In response, cells have evolved pathways to...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8396322/ https://www.ncbi.nlm.nih.gov/pubmed/34445553 http://dx.doi.org/10.3390/ijms22168850 |