R-Loops and Its Chro-Mates: The Strange Case of Dr. Jekyll and Mr. Hyde

Since their discovery, R-loops have been associated with both physiological and pathological functions that are conserved across species. R-loops are a source of replication stress and genome instability, as seen in neurodegenerative disorders and cancer. In response, cells have evolved pathways to...

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Detalles Bibliográficos
Autores principales: Uruci, Sidrit, Lo, Calvin Shun Yu, Wheeler, David, Taneja, Nitika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8396322/
https://www.ncbi.nlm.nih.gov/pubmed/34445553
http://dx.doi.org/10.3390/ijms22168850

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