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A Shortage of FTH Induces ROS and Sensitizes RAS-Proficient Neuroblastoma N2A Cells to Ferroptosis

Ferroptosis, an iron-dependent form of programmed cell death, has excellent potential as an anti-cancer therapeutic strategy in different types of tumors, especially in RAS-mutated ones. However, the function of ferroptosis for inhibiting neuroblastoma, a common child malignant tumor with minimal tr...

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Detalles Bibliográficos
Autores principales: Lu, Ruiqing, Jiang, Yinan, Lai, Xianxin, Liu, Shujie, Sun, Litao, Zhou, Zhong-Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8396332/
https://www.ncbi.nlm.nih.gov/pubmed/34445601
http://dx.doi.org/10.3390/ijms22168898