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A DNA Aptameric Ligand of Human Transferrin Receptor Generated by Cell-SELEX

General cancer-targeted ligands that can deliver drugs to cells have been given considerable attention. In this paper, a high-affinity DNA aptamer (HG1) generally binding to human tumor cells was evolved by cell-SELEX, and was further optimized to have 35 deoxynucleotides (HG1-9). Aptamer HG1-9 coul...

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Detalles Bibliográficos
Autores principales: Zhang, Nan, Bing, Tao, Shen, Luyao, Feng, Le, Liu, Xiangjun, Shangguan, Dihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8396340/
https://www.ncbi.nlm.nih.gov/pubmed/34445629
http://dx.doi.org/10.3390/ijms22168923