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A DNA Aptameric Ligand of Human Transferrin Receptor Generated by Cell-SELEX
General cancer-targeted ligands that can deliver drugs to cells have been given considerable attention. In this paper, a high-affinity DNA aptamer (HG1) generally binding to human tumor cells was evolved by cell-SELEX, and was further optimized to have 35 deoxynucleotides (HG1-9). Aptamer HG1-9 coul...
Autores principales: | Zhang, Nan, Bing, Tao, Shen, Luyao, Feng, Le, Liu, Xiangjun, Shangguan, Dihua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8396340/ https://www.ncbi.nlm.nih.gov/pubmed/34445629 http://dx.doi.org/10.3390/ijms22168923 |
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