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Palmitoylation of Prolactin-Releasing Peptide Increased Affinity for and Activation of the GPR10, NPFF-R2 and NPFF-R1 Receptors: In Vitro Study

The anorexigenic neuropeptide prolactin-releasing peptide (PrRP) is involved in the regulation of food intake and energy expenditure. Lipidization of PrRP stabilizes the peptide, facilitates central effect after peripheral administration and increases its affinity for its receptor, GPR10, and for th...

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Detalles Bibliográficos
Autores principales: Karnošová, Alena, Strnadová, Veronika, Holá, Lucie, Železná, Blanka, Kuneš, Jaroslav, Maletínská, Lenka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8396344/
https://www.ncbi.nlm.nih.gov/pubmed/34445614
http://dx.doi.org/10.3390/ijms22168904