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Suppression of LPS-Induced Inflammation and Cell Migration by Azelastine through Inhibition of JNK/NF-κB Pathway in BV2 Microglial Cells

The c-Jun N-terminal kinases (JNKs) are implicated in many neuropathological conditions, including neurodegenerative diseases. To explore potential JNK3 inhibitors from the U.S. Food and Drug Administration-approved drug library, we performed structure-based virtual screening and identified azelasti...

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Detalles Bibliográficos
Autores principales:	Nguyen, Phuong Linh, Bui, Bich Phuong, Duong, Men Thi Hoai, Lee, Kyeong, Ahn, Hee-Chul, Cho, Jungsook
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8396433/ https://www.ncbi.nlm.nih.gov/pubmed/34445767 http://dx.doi.org/10.3390/ijms22169061

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