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Targeting Lysosomes to Reverse Hydroquinone-Induced Autophagy Defects and Oxidative Damage in Human Retinal Pigment Epithelial Cells

In age-related macular degeneration (AMD), hydroquinone (HQ)-induced oxidative damage in retinal pigment epithelium (RPE) is believed to be an early event contributing to dysregulation of inflammatory cytokines and vascular endothelial growth factor (VEGF) homeostasis. However, the roles of antioxid...

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Detalles Bibliográficos
Autores principales: Abokyi, Samuel, Shan, Sze-Wan, Lam, Christie Hang-I, Catral, Kirk Patrick, Pan, Feng, Chan, Henry Ho-Lung, To, Chi-Ho, Tse, Dennis Yan-Yin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8396439/
https://www.ncbi.nlm.nih.gov/pubmed/34445748
http://dx.doi.org/10.3390/ijms22169042